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Soon Kil Ahn Selected Research

methyl- 4- (3- chloro- 4- methoxybenzylamino)- 8- (2- hydroxyethyl)- 7- methoxyquinazolin- 6- ylmethylcarbamate

1/2010Discovery of potent, selective, and orally bioavailable PDE5 inhibitor: Methyl-4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-ylmethylcarbamate (CKD 533).

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Soon Kil Ahn Research Topics

Disease

6Neoplasms (Cancer)
08/2017 - 09/2010
2Insulin Resistance
09/2018 - 01/2015
2Type 2 Diabetes Mellitus (MODY)
09/2018 - 01/2015
2Metabolic Syndrome (Dysmetabolic Syndrome X)
09/2018 - 01/2015
2Melanoma (Melanoma, Malignant)
08/2017 - 07/2012
2Erectile Dysfunction
01/2010 - 12/2008
1Body Weight (Weight, Body)
09/2018
1Colorectal Neoplasms (Colorectal Cancer)
08/2017
1Infections
03/2016
1Hypertension (High Blood Pressure)
01/2015
1Glucose Intolerance
01/2015
1Dyslipidemias (Dyslipidemia)
01/2015
1Abdominal Obesity
01/2015
1Glioma (Gliomas)
05/2014
1Myeloid Leukemia (Leukemia, Myelocytic)
03/2007
1Septic Shock (Toxic Shock Syndrome)
02/2006
1Endotoxemia
02/2006

Drug/Important Bio-Agent (IBA)

4Pharmaceutical PreparationsIBA
09/2018 - 07/2012
23-methyladenineIBA
03/2016 - 07/2012
2Protein Kinases (Protein Kinase)IBA
01/2013 - 01/2012
2N- ((3- (3- 9H- purin- 6- yl)pyridin- 2- ylamino)- 2,4- difluorophenyl)furan- 3- sulfonamideIBA
07/2012 - 01/2012
2ProdrugsIBA
11/2010 - 09/2010
2Tubulin ModulatorsIBA
11/2010 - 09/2010
2Valine (L-Valine)FDA Link
11/2010 - 09/2010
1Blood Glucose (Blood Sugar)IBA
09/2018
1LipidsIBA
09/2018
1INU-101IBA
09/2018
1Protein Isoforms (Isoforms)IBA
08/2017
1INU-152IBA
08/2017
1Beclin-1IBA
03/2016
1Small Interfering RNA (siRNA)IBA
03/2016
1DNA (Deoxyribonucleic Acid)IBA
03/2016
1Oxidoreductases (Dehydrogenase)IBA
01/2015
1GlucocorticoidsIBA
01/2015
1Hormones (Hormone)IBA
01/2015
14- (1- ((2- fluoro- N- methylphenylsulfonamido)methyl)cyclopropanecarboxamido)adamantane- 1- carboxamideIBA
01/2015
1Gentian Violet (Violet, Crystal)FDA Link
05/2014
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2014
1Sorafenib (BAY 43-9006)FDA Link
01/2013
1Proto-Oncogene Proteins B-rafIBA
07/2012
1Amino AcidsFDA Link
11/2010
1N- (4- (3- (1H- 1,2,4- triazol- 1- yl)- 4- (3,4,5- trimethoxybenzoyl)phenyl)thiazol- 2- yl)- 2- amino- 3- methylbutanamideIBA
09/2010
1methyl- 4- (3- chloro- 4- methoxybenzylamino)- 8- (2- hydroxyethyl)- 7- methoxyquinazolin- 6- ylmethylcarbamateIBA
01/2010
1QuinazolinesIBA
12/2008
1Phosphodiesterase 5 InhibitorsIBA
12/2008
1EthersIBA
03/2007
1higenamine (norcoclaurine)IBA
02/2006

Therapy/Procedure

1Oral Administration
09/2018
1Therapeutics
12/2008